来自仙人掌链霉菌的丝裂霉素C
粉末,含有氯化钠作为增溶剂
有货
基本信息
| 产品名称 | 来自仙人掌链霉菌的丝裂霉素C |
|---|---|
| 英文名称 | Mitomycin C from Streptomyces caespitosus |
| 规格或纯度 | 粉末,含有氯化钠作为增溶剂 |
| 运输条件 | 冰袋运输 |
| 生化机理 | 作用机制：该产物是专门针对鸟嘌呤核苷序列5′-CpG-3′的烷基化剂。它通过与DNA共价反应，在DNA互补链之间形成交联来抑制DNA合成。 这种相互作用可防止DNA互补链分离，从而抑制DNA复制。抗菌谱：丝裂霉素C具有很强的抗肿瘤活性，尤其是对艾氏腹水瘤细胞，对革兰氏阳性和革兰氏阴性细菌具有很强的杀菌作用。 |
一般描述
Description
Chemical structure: aziridineMitomycin C is produced by a strain of actinomyces,Streptomyces caespitosus. It contains three anticancer moieties, quinine, urethane, and aziridine groups. It is used to generate mitotically inactive feeder cells in cell culture systems, such as the mitotically inactive fibroblasts used in embryonic stem cell systems.
Preparation instructions
Mitomycin C is soluble in water at .5 mg/mL, with a pH of 6.0-7.5. It undergoes rapid degradation in acidic solutions with pH<6, and is mostly likely to retain activity in solutions with a pH between 6-9.
相关属性
| CAS编号 | 50-07-7 |
|---|---|
| 溶解性 | H2O：1 小瓶 + 4 mL，透明至微混浊，蓝色至紫色 |
| 储存温度 | 2-8°C储存 |
| MDL号 | MFCD00078109 |
| 分子量 | 334.33 |
| 分子式 | C15H18N4O5 |
| 品牌 | Jinpan |