Vincristine(Synonyms: Leurocristine; NSC-67574; 22-Oxovincaleukoblastine)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Vincristine (Synonyms: Leurocristine; NSC-67574; 22-Oxovincaleukoblastine)

Vincristine (Leurocristine) 是一种微管去稳剂。Vincristine (Leurocristine) 与微管蛋白结合，抑制微管的形成，从而抑制癌细胞的有丝分裂。Vincristine (Leurocristine) 用于治疗血液肿瘤，如白血病和淋巴瘤，以及儿童肉瘤。

Vincristine(Synonyms: Leurocristine; NSC-67574; 22-Oxovincaleukoblastine)

Vincristine Chemical Structure

CAS No. : 57-22-7

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Vincristine 的其他形式现货产品:

Vincristine sulfate

生物活性

Vincristine (Leurocristine) is a microtubule-destabilizing agent (MDA). Vincristine (Leurocristine) binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine (Leurocristine) is used to treat hematologic cancers, such as leukemia and lymphoma, and childhood sarcomas[1][2].

分子量

824.96

Formula

C46H56N4O10
CAS 号

57-22-7
中文名称

长春新碱
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Prota AE, et al. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13817-21.

    [2]. Beaver C, et al. Vincristine Minibag Administration: A Quality Improvement Project to Minimize Medical Errors. Clin J Oncol Nurs. 2018 Dec 1;22(6):669-672.

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