Sincalide ammonium(Synonyms: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sincalide ammonium (Synonyms: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium) 纯度: 99.90%

Sincalide ammonium (Cholecystokinin octapeptide ammonium) 是一种速效的胆囊收缩素 (CCK) 的氨基酸多肽激素类似物，可在胆囊造影术中静脉使用。Sincalide ammonium 是一种通过注射促进胆囊收缩并帮助诊断胆囊和胰腺疾病的物质。Sincalide ammonium 的肝胆生理作用是增加胆汁的分泌，使胆囊收缩并使 Oddi 的括约肌松弛，从而使胆汁排入十二指肠。

Sincalide ammonium(Synonyms: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium)

Sincalide ammonium Chemical Structure

CAS No. : 70706-98-8

规格 价格 是否有货 数量
1 mg ￥1100 In-stock
5 mg ￥3000 In-stock
10 mg ￥4800 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Sincalide ammonium 相关产品

•相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Sincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. The hepatobiliary physiologic effect of Sincalide ammonium is to increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum[1][2].

分子量

1160.30

Formula

C49H65N11O16S3
CAS 号

70706-98-8
Sequence Shortening

D-{SO3H-Tyr}-MGWMDF-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light, stored under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶解性数据
In Vitro: 

H2O : 12.5 mg/mL (10.77 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8618 mL 4.3092 mL 8.6185 mL
5 mM 0.1724 mL 0.8618 mL 1.7237 mL
10 mM 0.0862 mL 0.4309 mL 0.8618 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Maher KA. Kinevac (sincalide for injection)/Squibb Diagnostics. Gastroenterol Nurs. 1991 Oct;14(2):98-100.

    [2]. Ziessman HA. Sincalide: A Review of Clinical Utility, Proper Infusion Methodology, and Alternative Cholecystogogues. J Nucl Med Technol. 2019 Sep;47(3):210-212.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务