Medicarpin(Synonyms: 美迪紫檀素)

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Medicarpin (Synonyms: 美迪紫檀素) 纯度: ≥98.0%

Medicarpin 是一种从紫花苜蓿中分离出的类黄酮。Medicarpin 通过调节 P-gp 介导的药物外流，诱导白血病 P388 细胞凋亡 (apoptosis) 并克服多药耐药性。

Medicarpin(Synonyms: 美迪紫檀素)

Medicarpin Chemical Structure

CAS No. : 32383-76-9

规格 价格 是否有货 数量
1 mg ￥1950 In-stock
5 mg ￥4900 In-stock
10 mg   询价  
50 mg   询价  

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Medicarpin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

生物活性

Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of drugs[1].

体外研究
(In Vitro)

Medicarpin (90 µM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 µM for P388 and P388/DOX cells)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

270.28

Formula

C16H14O4
CAS 号

32383-76-9
中文名称

美迪紫檀素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Grégory Gatouillat, et al. Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells. medicine. 2015 Dec 1;22(13):1186-94.

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