Boc-aminooxy-amide-PEG4-propargyl

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Boc-aminooxy-amide-PEG4-propargyl 

Boc-aminooxy-amide-PEG4-propargyl 是一种不可降解 (non-cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Boc-aminooxy-amide-PEG4-propargyl

Boc-aminooxy-amide-PEG4-propargyl Chemical Structure

CAS No. : 2253965-01-2

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生物活性

Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

404.46

Formula

C18H32N2O8
CAS 号

2253965-01-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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