RET-IN-10

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

RET-IN-10 

RET-IN-10 是一种有效的 RET 抑制剂。RET 功能缺失突变导致先天性巨结肠,而其功能突变获得与多种人类肿瘤有关。RET-IN-10具有研究癌症疾病的潜力 (摘自专利 WO2021135938A1,化合物 18)。

RET-IN-10

RET-IN-10 Chemical Structure

CAS No. : 2662622-44-6

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生物活性

RET-IN-10 is a potent inhibitor of RET. RET loss of function mutations leads to Hirschsprung’s disease, while its gain of function mutations is associated with a variety of human tumors. RET-IN-10 has the potential for the research of cancer diseases (extracted from patent WO2021135938A1, compound 18)[1].

分子量

536.65

Formula

C29H28N8OS

CAS 号

2662622-44-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Anhu Li. Heterocyclic sulfoximine compounds and intermediates thereof, methods of preparation and applications. Patent WO2021135938A1.

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