Antitumor agent-41

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Antitumor agent-41 

Antitumor agent-41 是一种抗肿瘤剂，具有极好的抗迁移和抗侵袭活性。Antitumor agent-41 (compound N-12) 通过坏死和炎症通路发挥抗肿瘤活性。

Antitumor agent-41

Antitumor agent-41 Chemical Structure

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生物活性

Antitumor agent-41 (compound N-12), a potent antitumor agent, enhibits excellent antimigration and anti-invasion activity. Antitumor agent-41 (compound N-12) induces tumor inhibition via tumor necrosis and inflammatory response[1].

体外研究
(In Vitro)

Antitumor agent-41 (compound N-12) has obvious inhibitory activity on invasion at a concentration of 50 μM on A431 cell, and the inhibition rate was 36.6 ± 13.9% [1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

The half-life (T1/2) of antitumor-41 (compound N-12) is 56.80 h and systemic plasma clearance (CL) is 0.029 mL/h/mg.[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1369.46

Formula

C64H109IN2O21
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Juntao Wang, wt al. One-Pot Enzymatic Synthesis and Biological Evaluation of Ganglioside GM3 Derivatives as Potential Cancer Immunotherapeutics. J Med Chem. 2022 Feb 10;65(3):1883-1897.

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