Anticancer agent 30

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Anticancer agent 30 

Anticancer agent 30 (compound 6f-Z) 是一种 3-arylidene-2-oxindole 衍生物,一种选择性 CDK2 抑制剂,具有强效抗癌活性。

Anticancer agent 30

Anticancer agent 30 Chemical Structure

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生物活性

Anticancer agent 30 (compound 6f-Z), a 3-arylidene-2-oxindole derivative, is a selective CDK2 inhibitor with potent anticancer activity[1].

IC50 & Target[1]

CDK2

 

分子量

363.81

Formula

C22H15ClFNO

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hend A A Abd El-Wahab, et al. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies. Bioorg Chem. 2022 Jan 15;120:105622.

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