B-Raf IN 5 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

B-Raf IN 5

B-Raf IN 5 (化合物 3b) 是一种有效的蛋白激酶 B-Raf 抑制剂，IC₅₀ 为 2.0 nM。B-Raf IN 5 不与二级靶点 PXR 结合，并能抵抗快速代谢。B-Raf IN 5 具有研究癌症疾病的潜力。

B-Raf IN 5 Chemical Structure

CAS No. : 2648698-30-8

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生物活性	B-Raf IN 5 (compound 3b) is a potent inhibitor of protein kinase B-Raf with an IC₅₀ of 2.0 nM. B-Raf IN 5 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease^[1].
分子量	583.01
Formula	C₂₃H₁₈ClF₃N₆O₃S₂
CAS 号	2648698-30-8
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Schneider M, et al. Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding. J Med Chem. 2022;65(2):1552-1566.

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