Cathepsin L-IN-2(Synonyms: Z-Phe-Phe-FMK)

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Cathepsin L-IN-2 (Synonyms: Z-Phe-Phe-FMK)

Cathepsin L-IN-2 (Z-Phe-Phe-FMK) 是一种有效且不可逆的组织蛋白酶 L (cathepsin L) 和组织蛋白酶 B (cathepsin B) 抑制剂。

Cathepsin L-IN-2(Synonyms: Z-Phe-Phe-FMK)

Cathepsin L-IN-2 Chemical Structure

CAS No. : 108005-94-3

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生物活性

Cathepsin L-IN-2 (Z-Phe-Phe-FMK) is a potent and irreversible cathepsin L and cathepsin B inhibitor[1][2].

分子量

462.51

Formula

C27H27FN2O4
CAS 号

108005-94-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jonathan Frew, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21.

    [2]. Kirsi Ravanko, et al. Cysteine cathepsins are central contributors of invasion by cultured adenosylmethionine decarboxylase-transformed rodent fibroblasts. Cancer Res. 2004 Dec 15;64(24):8831-8.

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