Catalponol(Synonyms: 梓酚)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Catalponol (Synonyms: 梓酚)

Catalponol 是萘醌衍生物。Catalponol 通过诱导酪氨酸羟化酶 (tyrosine hydroxylase) 活性来增强多巴胺的生物合成。Catalponol 还可以提高 PC12 细胞中 cAMP 和酪氨酸羟化酶磷酸化的水平。

Catalponol(Synonyms: 梓酚)

Catalponol Chemical Structure

CAS No. : 34168-56-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2].

体外研究
(In Vitro)

In RAW 264.7 macrophage cells, Catalponol exhibits potent inhibitory effects with an IC50 value of 9.8 µM for inhibiting LPS-induced NO production[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

230.30

Formula

C15H18O2
CAS 号

34168-56-4
中文名称

梓酚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75.

    [2]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务