2′-Azido-2′-deoxyuridine(Synonyms: N3dUrd)

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2′-Azido-2′-deoxyuridine (Synonyms: N3dUrd)

2′-Azido-2′-deoxyuridine (N3dUrd) 是一种核糖核苷酸还原酶 (ribonucleotide reductase) 抑制剂。2′-Azido-2′-deoxyuridine 具有抗癌活性。

2

2′-Azido-2′-deoxyuridine Chemical Structure

CAS No. : 26929-65-7

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生物活性

2′-Azido-2′-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2′-Azido-2′-deoxyuridine has anti-cancer activity[1].

体外研究
(In Vitro)

2′-Azido-2′-deoxyuridine (N3dUrd) has IC50s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

269.21

Formula

C9H11N5O5
CAS 号

26929-65-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kang SH, et al. Biological activity and phosphorylation of 2‘-azido-2‘-deoxyuridine and 2‘-azido-2‘-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88.

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