Thiol-PEG12-acid

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Thiol-PEG12-acid 

Thiol-PEG12-acid 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Thiol-PEG12-acid

Thiol-PEG12-acid Chemical Structure

CAS No. : 2211174-73-9

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生物活性

Thiol-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

634.77

Formula

C27H54O14S
CAS 号

2211174-73-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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