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Waltonitone (Synonyms: 长梗秦艽酮)
Waltonitone 是一种从植物天竺葵中提取的乌斯烷型五环三萜。Waltonitone 在体外和体内均显着抑制肝癌细胞的生长并诱导细胞凋亡。
Waltonitone Chemical Structure
CAS No. : 1252676-55-3
规格 | 是否有货 | ||
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5 mg | 询价 | ||
10 mg | 询价 | ||
25 mg | 询价 |
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生物活性 |
Waltonitone is a ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. Waltonitone significantly inhibits hepatocellular carcinoma cells growth and induces apoptosis in vitro and in vivo[1]. |
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体外研究 (In Vitro) |
waltonitone (10 μM, 25 μM; for 48 hours) results in an increment of sub-G1 population in BEL-7402 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 (In Vivo) |
Waltonitone (i.v.; 20 mg/kg or 50 mg/kg; once every two days for 16 days) inhibits BEL-7402 tumor growth in male athymic mice (BALB/c nu/nu) in vivo[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
440.70 |
Formula |
C30H48O2 |
CAS 号 |
1252676-55-3 |
中文名称 |
长梗秦艽酮 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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