Rhapontigenin 3′-O-glucoside(Synonyms: 丹叶大黄素 3′-O-葡萄糖苷)

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Rhapontigenin 3′-O-glucoside (Synonyms: 丹叶大黄素 3′-O-葡萄糖苷) 纯度: 99.74%

Rhapontigenin 3′-O-glucoside 是 Rhapontigenin 的衍生物。Rhapontigenin 是一种有效的 P450 1A1 抑制剂,可用于预防癌症。

Rhapontigenin 3

Rhapontigenin 3′-O-glucoside Chemical Structure

CAS No. : 94356-22-6

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Rhapontigenin 3′-O-glucoside 相关产品

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生物活性

Rhapontigenin 3′-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent[1].

体外研究
(In Vitro)

Rhapontigenin exhibits a potent and selective inhibition of human P450 1A1 with an IC50 of 0.4 μM. Rhapontigenin shows 400-fold selectivity for P450 1A1 over P450 1A2 and 23-fold selectivity for P450 1A1 over P450 1B1[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

420.41

Formula

C21H24O9

CAS 号

94356-22-6

中文名称

丹叶大黄素 3′-O-葡萄糖苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Chun YJ, et al. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin. Drug Metab Dispos. 2001 Apr;29(4 Pt 1):389-93.

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