LSD1-IN-12

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

LSD1-IN-12 

LSD1-IN-12 (compound 2) 是一种有效的 LSD1 抑制剂，其 Ki 值分别为 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), 和 3.5 μM (MAO-B)。

LSD1-IN-12

LSD1-IN-12 Chemical Structure

CAS No. : 1228143-76-7

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生物活性

LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively[1].

IC50 & Target

MAO-A

2.3 μM (Ki)

MAO-B

3.5 μM (Ki)

分子量

252.31

Formula

C16H16N2O
CAS 号

1228143-76-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349.

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