Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,

红霉素

大环内酯类抗生素
效价 ≥850 μg/mg

有货

Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,

CAS编号 114-07-8 | 品牌:Jinpan
Erythromycin

MSDS

质检证书(CoA)

相似产品

  • 分子式 C37H67NO13
  • 分子量733.93
  • Beilstein号 75279
  • EC号 204-040-1
  • MDL号 MFCD00084654
  • PubChem编号 12560

货号 (SKU) 包装规格 是否现货 价格 数量
E105345-1g 1g 现货 Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,  
E105345-5g 5g 现货 Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,  
E105345-25g 25g 现货 Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,  
E105345-100g 100g 现货 Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,  
E105345-500g 500g 现货 Cas(114-07-8), 红霉素, 红霉素碱,Erythromycin,  

基本信息

产品名称 红霉素
英文名称 Erythromycin
别名 红霉素;红霉素碱
英文别名 (-)-Erythromycin ;Abomacetin
规格或纯度 效价 ≥850 μg/mg
运输条件 常规运输
生化机理 在转肽步骤抑制延长期,靠结合到核糖体上抑制细菌蛋白合成,对细菌诱发红霉素抗性。抗菌谱: 革兰氏阴性和阳性细菌。 属大环内酯抗生素(Macrolide antibiotic) .大环内酯类抗生素。抑制细胞色素p450 3A4和P-糖蛋白。结合50S核糖体亚基并抑制革兰氏阳性和革兰氏阴性细菌中的蛋白质合成。

一般描述

Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes. A macrolide antibiotic protein synthesis inhibitor. Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjμgate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes.
A macrolide antibiotic protein synthesis inhibitor. Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

相关属性

CAS编号 114-07-8
敏感性 对湿度敏感
比旋光度 -74 ° (C=2, EtOH)
熔点 138-140°C
溶解性 熔于乙醇、甲醇、丙酮、氯仿、乙腈和乙酸乙酯,中等程度溶于醚、二氯甲烷和乙酸戊酯。难溶于水。微有引湿性,无臭,味苦。遇酸不稳定。水中溶解度:+/- 3 MG/ML。
储存温度 充氩
RTECS KF437500
MDL号 MFCD00084654
密度 1.2
分子量 733.93
分子式 C37H67NO13
EC号 204-040-1
品牌 Jinpan
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PubChem CID 12560