K252b,蛋白激酶抑制剂
基本信息
产品名称 | K252b,蛋白激酶抑制剂 |
---|---|
英文名称 | K252b |
别名 | Staurosporine Aglycone |
英文别名 | Staurosporine Aglycone |
规格或纯度 | ≥97%(HPLC) |
运输条件 | 超低温冰袋运输 |
一般描述
K252B: an inhibitor of protein kinase A, C, G K-252b is a general, cell permeable protein kinase inhibitor which acts by binding to the ATP binding domain of the kinase. K-252b is a potent inhibitor of CaMKII (Ca2+/calmodulin kinase II), MYLK (myosin light chain kinase, Ki=0.147 μM), PKA (cAMP- dependent protein kinase, Ki=0.09 μM), PKC (protein kinase C, Ki=0.02 μM), and cGKI (cGMP-dependent protein kinase, Ki=0.1 μM).An antibiotic and a strong inhibitor of protein kinase C (PKC)
K252B: an inhibitor of protein kinase A, C, G K-252b is a general, cell permeable protein kinase inhibitor which acts by binding to the ATP binding domain of the kinase. K-252b is a potent inhibitor of CaMKII (Ca2+/calmodulin kinase II), MYLK (myosin light chain kinase, Ki=0.147 μM), PKA (cAMP- dependent protein kinase, Ki=0.09 μM), PKC (protein kinase C, Ki=0.02 μM), and cGKI (cGMP-dependent protein kinase, Ki=0.1 μM).
An antibiotic and a strong inhibitor of protein kinase C (PKC)
相关属性
CAS编号 | 99570-78-2 |
---|---|
敏感性 | 对光线和湿度敏感,易吸潮 |
熔点 | 318.16°C |
沸点 | 769.82 °C at 760 mmHg |
溶解性 | Soluble in DMSO (1 mg/ml), DMF (1 mg/ml), and methanol (2 mg/ml). |
储存温度 | -20°C储存 |
密度 | 1.78 |
分子量 | 453.5 |
分子式 | C26H19N3O5 |
品牌 | Jinpan |
PubChem CID | 101713435 |