Cas(149-29-1), 棒曲霉素, 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮,Patulin,

棒曲霉素

真菌真菌毒素,DNA破坏剂并诱导ROS产生
99%

有货

Cas(149-29-1), 棒曲霉素, 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮,Patulin,

CAS编号 149-29-1 | 品牌:Jinpan
Patulin

MSDS

质检证书(CoA)

相似产品

  • 分子式 C7H6O4
  • 分子量154.12
  • Beilstein号 149675
  • EC号 200-663-8
  • MDL号 MFCD00005858
  • PubChem编号 4696

货号 (SKU) 包装规格 是否现货 价格 数量
P113515-1mg 1mg 现货 Cas(149-29-1), 棒曲霉素, 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮,Patulin,  
P113515-5mg 5mg 现货 Cas(149-29-1), 棒曲霉素, 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮,Patulin,  
P113515-25mg 25mg 现货 Cas(149-29-1), 棒曲霉素, 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮,Patulin,  

基本信息

产品名称 棒曲霉素
英文名称 Patulin
别名 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮
英文别名 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one;Clavacin;Claviformin;Mycoin;Penicidin;Expansin;Leucopin;Gigantin
应用 An inhibitor of protein prenylation
规格或纯度 99%
运输条件 超低温冰袋运输
生化机理 真菌霉菌毒素,DNA破坏剂,诱导ROS产生。体外EGR-1依赖性ATF3上调诱导细胞凋亡。抗菌,致癌,诱变和抗癌剂。体内具有活性

一般描述

Patulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies sμggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.An inhibitor of protein prenylation

Patulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies suggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.
An inhibitor of protein prenylation

相关属性

CAS编号 149-29-1
敏感性 对光敏感;对湿度敏感
熔点 108-111°C
溶解性 Soluble in water, 100% ethanol (25 mg/mL), ethyl acetate (50 mg/mL), amyl acetate, DMSO (10 mg/mL), acetone, ethyl ether (sparingly), benzene (sparingly), and dichloromethane (10 mg/mL)
储存温度 避光,-20°C储存,干燥
MDL号 MFCD00005858
密度 1.52
分子量 154.12
分子式 C7H6O4
EC号 200-663-8
品牌 Jinpan
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PubChem CID 4696