2,2-二溴-N-[1,3-二羟基-1-(4-硝基苯基)-2-丙基]乙酰胺

Bromamphenicol 是一种半合成的氯霉素类似物，其中二氯乙酰胺被二溴乙酰胺取代，最早于1950年被报道。溴苯丙胺醇的抗生素活性较弱。用氯霉素进行的比较晶体学分析有助于确定核糖体上乙酰胺结合区的SAR。最近，这种关系用于证明氯霉素与革兰氏阴性细菌中DraE毒力因子的结合与核糖体上氯霉素结合位点无关。

Bromamphenicol is a semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide, first reported in 1950. Bromamphenicol possesses weak antibiotic activity. Comparative crystallography with chloramphenicol helped defined the SARs of the acetamide binding region on the ribosome. More recently, this relationship was used to demonstrate that chloramphenicol binding to DraE virulence factors in Gram negative bacteria was independent of chloramphenicol binding site on the ribosome.