阿兹达芬尼醇
半合成氯霉素
≥95%
有货
基本信息
产品名称 | 阿兹达芬尼醇 |
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英文名称 | Azidamfenicol |
英文别名 | Azidoamphenicol; Leukomycin N |
规格或纯度 | ≥95% |
运输条件 | 超低温冰袋运输 |
一般描述
阿齐达芬尼科尔是一种半合成的氯霉素,其中的硝基部分被甲基砜取代,二氯乙酰胺被叠氮基乙酰胺取代,该化合物于1959年在拜耳公司首先合成。阿达芬尼醇通过与50S核糖体的23S亚基结合而起作用,从而抑制蛋白质的合成。阿齐达芬尼醇几乎没有受到研究关注,仅引用了少量文献。
Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in 1959. Azidamfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Azidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Azidamfenicol has received little research attention with only a few literature citations.
相关属性
CAS编号 | 13838-08-9 |
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储存温度 | -20°C储存 |
分子量 | 295.25 |
分子式 | C11H13N5O5 |
品牌 | Jinpan |
Smiles | C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)CN=[N+]=[N-])O)[N+](=O)[O-] |
PubChem CID | 62858 |