A54556B
对革兰氏阳性和革兰氏阴性细菌有效的抗菌剂
有货
基本信息
| 产品名称 | A54556B |
|---|---|
| 英文名称 | A54556B |
| 运输条件 | 超低温冰袋运输 |
一般描述
A54556B是分离自链霉菌的不寻常的二肽，具有三烯酮侧链。A54556B是针对革兰氏阳性和革兰氏阴性细菌（包括MRSA）的有效抗菌剂。它是最近重新发现的酰基肽肽（ADEP）抗生素的成员，该肽通过激活和失活Clp家族蛋白发挥作用。ADEP被认为是开发新一代抗药性抗生素的重要线索。
A54556B is an unusual depsipeptide isolated from|Streptomyces|sp., featuring a trienone side chain. A54556B is a potent antibacterial against Gram positive and Gram negative bacteria including MRSA. It is a member of the recently re-discovered acyldepsipeptide (ADEP) antibiotics that act by activating and disregulating Clp-family proteins. ADEPs are considered important leads in the development of new generations of antibiotics against resistant bacteria.
相关属性
| CAS编号 | 95398-44-0 |
|---|---|
| 储存温度 | -20°C储存 |
| 分子量 | 704.81 |
| 分子式 | C37H48N6O8 |
| 品牌 | Jinpan |
| Smiles | C1C[C@@H]3N(C1)C(=O)[C@H](C)NC([C@H](C)N(C)C([C@@H]2CCCN2C([C@H](COC3=O)NC([C@H](CC4=CC=CC=C4)NC(=O)C=CC=CC=CC)=O)=O)=O)=O |
| PubChem CID | 102079728 |