Gilvocarcin M
95%
有货
基本信息
| 产品名称 | Gilvocarcin M |
|---|---|
| 英文名称 | Gilvocarcin M |
| 规格或纯度 | 95% |
| 运输条件 | 超低温冰袋运输 |
一般描述
Gilvocarcin M是从| Streptomyces |中分离的C-糖苷类抗肿瘤活性物质复合物的次要类似物。Gilvocarcin M在8位上含有一个甲基，其活性低于乙烯基类似物Gilvocarcin V，后者被认为是人类拓扑异构酶II的抑制剂。Gilvocarcin M具有强大的抗菌，抗真菌，抗病毒和抗肿瘤活性。关于gilvocarcins的最新研究表明，它们充当了DNA与组蛋白的光活化交联剂。
Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from|Streptomyces|. Gilvocarcin M contains a methyl group in the 8-position and is less active than the vinyl analogue Gilvocarcin V , which is thought to act as an inhibitor of human topoisomerase II. Gilvocarcin M displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research on the gilvocarcins suggests that they act as photoactivated crosslinkers of DNA to histones.
相关属性
| CAS编号 | 77879-89-1 |
|---|---|
| 折光率 | n20D1.68 (Predicted) |
| 熔点 | 319.72° C (Predicted) |
| 沸点 | 794.64° C at 760 mmHg (Predicted) |
| 溶解性 | Soluble in DMF, DMSO, methanol (slightly), and 100% ethanol (slightly). |
| 储存温度 | -20°C储存 |
| RTECS | DI2250000 |
| 密度 | 1.45 g/cm3(Predicted) |
| 分子量 | 482.48 |
| 分子式 | C26H26O9 |
| 品牌 | Jinpan |
| Smiles | CC1C(C(C(C(O1)C2=C3C(=C(C=C2)O)C(=CC4=C3OC(=O)C5=CC(=CC(=C54)OC)C)OC)O)O)O |
| PubChem CID | 53801 |