泰利霉素
基本信息
| 产品名称 | 泰利霉素 |
|---|---|
| 英文名称 | Telithromycin |
| 别名 | 泰利霉素；替利霉素；红霉酮(特利霉素) |
| 英文别名 | (1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone |
| 规格或纯度 | 97% |
| 运输条件 | 超低温冰袋运输 |
一般描述
Product Describtion:
Telithromycin(HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Target: AntibacterialTelithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and blocks the progression of the growing polypeptide chain. Telithromycin has over 10 times higher affinity to the subunit 50S than erythromycin. In addition, telithromycin strongly bind simultaneously to two domains of 23S RNA of the 50 S ribosomal subunit, where older macrolides bind strongly only to one domain and weakly to the second domain. Telithromycin can also inhibit the formation of ribosomal subunits 50S and 30S. From Wikipedia.
相关属性
| CAS编号 | 191114-48-4 |
|---|---|
| 溶解性 | DMSO : 100 mg/mL (123.15 mM, Need ultrasonic) |
| 储存温度 | -20°C储存 |
| 分子量 | 812 |
| 分子式 | C43H65N5O10 |
| 品牌 | Jinpan |
| 关联CAS | 173838-31-8 |