磷霉素二钠盐
基本信息
| 产品名称 | 磷霉素二钠盐 |
|---|---|
| 英文名称 | Fosfomycin Disodium Salt |
| 别名 | (1R,2S)-1,2-环氧丙基磷酸二钠盐 |
| 英文别名 | (1R,2S)-1,2-Epoxypropylphosphonic Acid Disodium Salt; Disodium (1R,2S)-1,2-Epoxypropylphosphonate；Fosfomycin disodium；Phosphomycin disodium salt；(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, disodium salt |
| 应用 | Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine |
| 规格或纯度 | >98.0%(HPLC) |
| 运输条件 | 冰袋运输 |
| 生化机理 | Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.Broad spectrum antimicrobial agent. Inhibits cell wall synthesis in Gram-negative and Gram-positive bacteria. Pharmacologically active following intravenous administration. Crosses the blood-brain barrier. |
一般描述
Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine
Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine
相关属性
| CAS编号 | 26016-99-9 |
|---|---|
| 敏感性 | 对热敏感 |
| 比旋光度 | -5° (C=5,H2O) |
| 溶解性 | Freely soluble in water or aqueous solution；Slightly soluble in methanol |
| 储存温度 | 2-8°C储存 |
| MDL号 | MFCD22741288 |
| 分子量 | 182.02 |
| 分子式 | C3H5Na2O4P |
| EC号 | 247-409-2 |
| 品牌 | Jinpan |
| 备注 | 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| 关联CAS | 23155-02-4 |
| PubChem CID | 73491 |