头孢磺啶钠盐水合物
基本信息
| 产品名称 | 头孢磺啶钠盐水合物 |
|---|---|
| 英文名称 | Cefsulodin Sodium Salt Hydrate |
| 别名 | 头孢磺吡苄钠盐水合物；头孢磺啶钠；达克舒林；磺吡芐头孢菌素；头孢磺吡芐；头孢磺吡酮 |
| 英文别名 | Cefsulfen sodium salt hydrate；Cefsulodin sodium,；Sulcephalosporin；4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-pyridinium inner salt, monosodium salt |
| 应用 | A β lactam antibiotic. |
| 规格或纯度 | ≥95.0%(HPLC) |
| 运输条件 | 超低温冰袋运输 |
一般描述
Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. The compound displays a mechanism of action like many β lactam antibiotics throμgh inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Throμgh the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-resistant mutants of Pseudomonas aerμginosa PAO4089 growth displayed that Cefsulodin sodium salt hydrate may compete with PBP3 in addtion to PBP1A and PBP1B. A β lactam antibiotic.
Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. The compound displays a mechanism of action like many β lactam antibiotics through inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Through the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-resistant mutants of Pseudomonas aeruginosa PAO4089 growth displayed that Cefsulodin sodium salt hydrate may compete with PBP3 in addtion to PBP1A and PBP1B.
A β lactam antibiotic.
相关属性
| CAS编号 | 52152-93-9 |
|---|---|
| 敏感性 | 对 湿度、热敏感 |
| 折光率 | +16.0 to +20.0 deg(C=1, H2O) |
| 溶解性 | 50 mg/m H2O. |
| 储存温度 | -20°C储存,充氩 |
| MDL号 | MFCD07793338 |
| 分子量 | 554.52(as Anhydrous) |
| 分子式 | C22H19N4NaO8S2·xH2O |
| 品牌 | Jinpan |
| PubChem CID | 656644 |