克拉霉素
大环内酯类抗生素
≥98%
有货
基本信息
产品名称 | 克拉霉素 |
---|---|
英文名称 | Clarithromycin |
别名 | 克拉霉素 |
英文别名 | Biaxin; Biaxin XL; Clarosip; Klaricid; Cyllind;6-O-Methylerythromycin; A-56268; TE-03 |
应用 | A macrolide antibiotic and protein synthesis inhibitor |
规格或纯度 | ≥98% |
运输条件 | 冰袋运输 |
生化机理 | Clarithromycin is a 14-member ring macrolide antibiotic and 6-O-methyl derivative of erythromycin. Clarithromycin has reported bacteriostatic action against gram-positive bacteria and some gram-negative bacteria including anaerobes. Similar to other macrolide antibiotics, this antibiotic is believed to function via binding of the ribosome within the microorganism. Studies have noted that Clarithromycin appears to bind specifically to the 50S ribosomal subunit, thus inhibiting DNA translation and inhibiting bacterial growth. This compound is both a substrate and inhibitor of CYP3A4.Macrolide antibiotic. Interferes with protein synthesis by reversibly binding to the 50S subunit in the bacterial ribosome. Regulates matrix metalloprotease activity. Bacteriostatic and bactericidal effects in vitro and in vivo . |
一般描述
Clarithromycin 是一种大环内酯类抗生素,是CYP3A4抑制剂。A macrolide antibiotic and protein synthesis inhibitor
Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor.
A macrolide antibiotic and protein synthesis inhibitor
相关属性
CAS编号 | 81103-11-9 |
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比旋光度 | -92°C |
熔点 | 225°C |
溶解性 | Soluble in ethanol (<1 mg> |
储存温度 | 2-8°C储存 |
RTECS | KF4997000 |
MDL号 | MFCD00865140 |
分子量 | 747.95 |
分子式 | C38H69NO13 |
品牌 | Jinpan |
备注 | 如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,这些产品最多可以使用一周。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
PubChem CID | 84029 |