阿扎那韦硫酸盐
≥98%
有货
基本信息
| 产品名称 | 阿扎那韦硫酸盐 |
|---|---|
| 英文名称 | Atazanavir Sulfate |
| 别名 | 阿扎那韦硫酸盐；(3S,8S,9S,12S)-9-苄基-3,12,二叔丁基-8-羟基-4,11-二氧代-6-(对-2-吡啶基苄基)-2,5,6,10,13-五氮杂十四烷二酸二甲酯硫酸盐 [(5S,8S,9S,14S)-8-苄基-5-(叔丁基)-9-羟基-15,15-二甲基-3,6,13-三氧代-11-[4-(吡啶-2-基)苄基]-2-氧杂-4,7,11,12-四氮杂十六烷-14-基]氨基甲酸甲酯硫酸盐 |
| 英文别名 | BMS-232632-05; Reyataz;BMS 232632 sulfate; BMS-232632 sulfate; BMS232632 sulfate;Dimethyl (3S,8S,9S,12S)-9-Benzyl-3,12,di-tert-butyl-8-hydroxy-4,11-dioxo-6-(p-2-pyridylbenzyl)-2,5,6,10,13-pentaazatetradecanedioate Sulfate;Dimethyl (3S,8S,9S,12S)-9-Benzyl- |
| 应用 | A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. |
| 规格或纯度 | ≥98% |
| 运输条件 | 冰袋运输 |
| 生化机理 | Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drμg combinations. |
一般描述
Atazanavir Sulfate是一种HIV protease（HIV蛋白酶）抑制剂，抑制HIV Atazanavir，Ki值为2.66 nM。A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.
Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM.
A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.
相关属性
| CAS编号 | 229975-97-7 |
|---|---|
| 敏感性 | 对空气敏感，对热敏感 |
| 溶解性 | Soluble in water (4-5 mg/ml), and methanol. |
| 储存温度 | 2-8°C储存,充氩 |
| MDL号 | MFCD08067748 |
| 分子量 | 802.93 |
| 分子式 | C38H52N6O7.H2SO4 |
| 品牌 | Jinpan |
| 备注 | 5mg、50mg、250mg、10mg卖完停产，不再备货 |
| PubChem CID | 158550 |