新霉素 三硫酸盐 水合物
适用于植物细胞培养
有货
基本信息
产品名称 | 新霉素 三硫酸盐 水合物 |
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英文名称 | Neomycin trisulfate salt hydrate |
规格或纯度 | 适用于植物细胞培养 |
生化机理 | 作用方式:该产品通过和30S以及50S亚基结合,引起错编,抑制蛋白质合成过程的起始和延长。 新霉素也可阻断电压敏感的Ca 2+ 通道,而不会影响神经元中Na + /Ca 2+ 逆向转运蛋白。 抗菌谱:新霉素能够作用于革兰氏阳性和阴性细菌。 |
一般描述
制备说明
Neomycin sulfate is soluble in H 2 O at 50 mg/mL, yielding a clear solution.
General Description
Chemical structure: aminoglycoside
Application
Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells transformed using the neo selectable marker gene, and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins. It is recommended for use in cell culture applications at 50 mg/L.
相关属性
CAS编号 | 1405-10-3 |
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比旋光度 | 56° (C=10,H2O) |
Reaxys-RN | 9468364 |
RTECS | QP4375000 |
分子量 | 908.88 |
分子式 | C23H46N6O13·3H2SO4·xH2O |
EC号 | 215-773-1 |
品牌 | Jinpan |
备注 | 注意: Stock solutions should be filter sterilized and stored at 2-8°C, and are stable at 37°C for 5 days. A 1 mg/mL neomycin solution in .1 M phosphate buffer, pH 8.0 should be used within 14 days when stored at 0-5°C. Solutions should be protected fr |
PubChem CID | 197162 |