壮观霉素
基本信息
产品名称 | 壮观霉素 |
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英文名称 | Spectinomycin |
规格或纯度 | 现成溶液,100mg/mL,DMSO/H₂O,1:1 |
生化机理 | 作用方式:通过干扰肽基 tRNA 的转位抑制蛋白质合成(延伸)。抗菌谱:革兰氏阴性和革兰氏阳性菌(仅包括淋球菌)。抗性机理:rpsE(核糖体蛋白 S5 的基因)的突变可阻止壮观霉素的结合。 |
一般描述
Description
Chemical structure: aminoglycosideSpectinomycin is an aminocyclitol antibiotic derived fromStreptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused byPasteurella multocidaandMannheimia haemolytica,and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
Preparation instructions
Stock solutions should be prepared at 10 mg/mL in water and 0.2 μm filtered.
Description
Chemical structure: aminoglycosideSpectinomycin is an aminocyclitol antibiotic derived fromStreptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused byPasteurella multocidaandMannheimia haemolytica,and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
Preparation instructions
Stock solutions should be prepared at 10 mg/mL in water and 0.2 μm filtered.
相关属性
溶解性 | DMSO/H2O,1:1:可溶性 100mg/mL |
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储存温度 | 充氩,干燥 |
MDL号 | MFCD04041129 |
品牌 | Jinpan |