来自卡那霉素链霉菌的卡那霉素溶液
基本信息
| 产品名称 | 来自卡那霉素链霉菌的卡那霉素溶液 |
|---|---|
| 英文名称 | Kanamycin solution from Streptomyces kanamyceticus |
| 规格或纯度 | 50-60 mg/mL，0.9%NaCl，生物制剂，液体，过滤0.1μm，适用于细胞培养 |
| 运输条件 | 冰袋运输 |
| 生化机理 | Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding. Mode of Resistance: Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes. Antimicrobial spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma. |
一般描述
General Description
Kanamycin sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus . It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 2 mL/L.
Application
Kanamycin solution from Streptomyces kanamyceticus has been used: to induce deafness in neonatal rats as an endothelial growth medium component for culturing human umbilical vein endothelial cells (HUVECs) as medium component for Mycobacteria Cultures and Top10 E coli cells
相关属性
| CAS编号 | 25389-94-0 |
|---|---|
| 比旋光度 | 117.5 ° (C=1, H2O) |
| 熔点 | 250°C(dec.)(lit.) |
| 储存温度 | 2-8°C储存 |
| Reaxys-RN | 3874279 |
| RTECS | NZ3225030 |
| 分子量 | 582.58 |
| 分子式 | C18H36N4O11·H2SO4 |
| 品牌 | Jinpan |
| 备注 | 注意: Solutions are stable at 37°C for approximately 5 days. Aqueous stock solutions can be stored at Store at 2-8°C for long term storage. |
| Smiles | ;OC[C@H]1O[C@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@@H](O)[C@H]3O)[C@H]2O)[C@H](O)[C@H](N)[C@@H]1O;OC[C@H]1O[C@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)[C@H](O)[C@@H](N)[C@@H]1O.OS(=O)(=O |
| 关联CAS | 70560-51-9 |
| PubChem CID | 441374 |