AMXI-5001

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

AMXI-5001  纯度: 98.43%

AMXI-5001 是一种有效的、具有口服活性的 parp1/2 和微管聚合抑制剂。MXI-5001 对多种人类癌细胞表现出选择性抗肿瘤细胞毒性,其 IC50s 比现有的临床 PARP1/2 抑制剂低得多。AMXI-5001 诱导已建立的肿瘤完全消退,包括非常大的肿瘤。

AMXI-5001

AMXI-5001 Chemical Structure

CAS No. : 2170491-77-5

规格 价格 是否有货 数量
5 mg ¥6500 In-stock
10 mg ¥10500 In-stock
25 mg ¥21500 In-stock
50 mg ¥34500 In-stock
100 mg ¥55000 In-stock
200 mg   询价  
500 mg   询价  

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AMXI-5001 相关产品

相关化合物库:

  • Bioactive Compound Library Plus
  • Cell Cycle/DNA Damage Compound Library
  • Anti-Cancer Compound Library
  • Anti-Aging Compound Library
  • Cytoskeleton Compound Library
  • Anti-Lung Cancer Compound Library

生物活性

AMXI-5001 is a potent, orally active, and dual parp1/2 and microtubule polymerization inhibitor. MXI-5001 exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors. AMXI-5001 induces complete regression of established tumors, including exceedingly large tumors[1].

分子量

457.46

Formula

C25H20FN5O3

CAS 号

2170491-77-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Lemjabbar-Alaoui H, et al. AMXI-5001, a novel dual parp1/2 and microtubule polymerization inhibitor for the treatment of human cancers. Am J Cancer Res. 2020;10(8):2649-2676.

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