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Thalidomide-PEG2-C2-NH2 TFA (Synonyms: Thalidomide-NH-PEG2-C2-NH2 TFA) 纯度: 98.85%
Thalidomide-PEG2-C2-NH2 TFA 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker。
Thalidomide-PEG2-C2-NH2 TFA Chemical Structure
CAS No. : 2097509-36-7
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| Free Sample (0.1-0.5 mg) | Apply now | ||
| 25 mg | ￥3500 | In-stock | |
| 100 mg | ￥8000 | In-stock | |
| 200 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Thalidomide-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
518.44 |
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| Formula |
C21H25F3N4O8 |
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| CAS 号 |
2097509-36-7 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
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| 参考文献 |
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