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Thalidomide-O-amido-PEG3-C2-NH2 (Synonyms: Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14)
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker。
Thalidomide-O-amido-PEG3-C2-NH2 Chemical Structure
CAS No. : 1957236-20-2
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Thalidomide-O-amido-PEG3-C2-NH2 的其他形式现货产品:
生物活性 |
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. Thalidomide-O-amido-PEG3-C2-NH2 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
506.51 |
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Formula |
C23H30N4O9 |
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CAS 号 |
1957236-20-2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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