SuO-Glu-Val-Cit-PAB-MMAE

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SuO-Glu-Val-Cit-PAB-MMAE 

SuO-Glu-Val-Cit-PAB-MMAE 由可降解 (cleavable) 的 ADC linker (SuO-Glu-Val-Cit-PAB) 和 MMAE 组成，MMAE 是一种有效的微管 (tubulin) 抑制剂。SuO-Glu-Val-Cit-PAB-MMAE可用于合成抗体偶联药物 (ADC)。

SuO-Glu-Val-Cit-PAB-MMAE

SuO-Glu-Val-Cit-PAB-MMAE Chemical Structure

CAS No. : 1895916-24-1

规格 价格 是否有货
1 mg ￥11500 询问价格 & 货期
5 mg ￥26500 询问价格 & 货期

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生物活性

SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Auristatin

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1334.60

Formula

C67H103N11O17
CAS 号

1895916-24-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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