Mal-NH2 TFA

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Mal-NH2 TFA 

Mal-NH2 (TFA) 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

Mal-NH2 TFA

Mal-NH2 TFA Chemical Structure

CAS No. : 146474-00-2

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100 mg ￥500 In-stock
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生物活性

Mal-NH2 (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

254.16

Formula

C8H9F3N2O4
CAS 号

146474-00-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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