N-Acetyl-Calicheamicin(Synonyms: N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin)

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N-Acetyl-Calicheamicin (Synonyms: N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin) 纯度: 99.39%

N-Acetyl-Calicheamicin是一类高活性抗肿瘤的抗生素。

N-Acetyl-Calicheamicin(Synonyms: N-Acetyl-Calicheamicin γ;  N-Acetyl-γ-calicheamicin)

N-Acetyl-Calicheamicin Chemical Structure

CAS No. : 108212-76-6

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5 mg ¥65000 In-stock
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生物活性

N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: Antibacterial N-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.

分子量

1410.39

Formula

C57H76IN3O22S4

CAS 号

108212-76-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献
  • [1]. Stasi R, et al. Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia. Cancer Treat Rev. 2008 Feb;34(1):49-60.

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