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2-Deoxy-2-fluoro-L-fucose (Synonyms: 2-脱氧-2-氟-L-岩藻糖) 纯度: 99.56%
2-Deoxy-2-fluoro-L-fucose 是一种 L-岩藻糖类似物,是岩藻糖基化 (fucosylation) 抑制剂。2-Deoxy-2-fluoro-L-fucose 抑制哺乳动物细胞中 GDP-岩藻糖的从头合成。Fucosylation 是许多人类癌症进展的相对明确的生物标志物,例如,胰腺癌和肝细胞癌。
![2-Deoxy-2-fluoro-L-fucose Chemical Structure 2-Deoxy-2-fluoro-L-fucose(Synonyms: 2-脱氧-2-氟-L-岩藻糖)](http://www.fluoroprobe.com/wp-content/uploads/2022/05/hy-116705.gif)
2-Deoxy-2-fluoro-L-fucose Chemical Structure
CAS No. : 70763-62-1
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥2200 | In-stock | |
10 mg | ¥3600 | In-stock | |
25 mg | ¥7200 | In-stock | |
50 mg | ¥11500 | In-stock | |
100 mg | 询价 | ||
200 mg | 询价 |
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2-Deoxy-2-fluoro-L-fucose 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Anti-Cancer Compound Library
- Anti-Liver Cancer Compound Library
生物活性 |
2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma[1]. |
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体外研究 (In Vitro) |
2-Deoxy-2-fluoro-L-fucose (2FF) (100-500 μM)) suppresses fucosylation in 4T1 cells[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
166.15 |
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Formula |
C6H11FO4 |
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CAS 号 |
70763-62-1 |
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中文名称 |
2-脱氧-2-氟-L-岩藻糖 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (601.87 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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