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Thalidomide-Piperazine-PEG2-NH2 diTFA 纯度: 99.76%
Thalidomide-Piperazine-PEG2-NH2 diTFA 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。
Thalidomide-Piperazine-PEG2-NH2 diTFA Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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25 mg | ¥5600 | In-stock | |
50 mg | ¥8800 | In-stock | |
100 mg | ¥13200 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
701.57 |
Formula |
C27H33F6N5O10 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
参考文献 |
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