Bis-PEG3-acid | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Bis-PEG3-acid

Bis-PEG3-acid 是一种 PROTAC linker，属于 PEG 类。Bis-PEG3-acid 可用于合成一系列 PROTAC 分子。

Bis-PEG3-acid Chemical Structure

CAS No. : 96517-92-9

规格	价格	是否有货
100 mg	￥800	In-stock
200 mg		询价
500 mg		询价

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生物活性

Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target^[1]

PEGs

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

250.25

Formula

C₁₀H₁₈O₇

CAS 号

96517-92-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298.

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