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Bithionol sulfoxide (Synonyms: 硫双二氯酚亚砜) 纯度: 98.65%
Bithionol sulfoxide(Bitin-S)是一抗寄生虫化合物,被研究显示具有抗癌活性。
Bithionol sulfoxide Chemical Structure
CAS No. : 844-26-8
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥2750 | In-stock | |
500 mg | ¥2500 | In-stock | |
1 g | 询价 | ||
5 g | 询价 |
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Bithionol sulfoxide 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Anti-Infection Compound Library
- Anti-Cancer Compound Library
- Antiparasitic Compound library
生物活性 |
Bithionol sulfoxide(Bitin-S) is a clinically approved anti-parasitic drug; has been shown to inhibit solid tumor growth in several preclinical cancer models. IC50 value: Target: anticaner agent Bithionol caused dose dependent cytotoxicity against all ovarian cancer cell lines tested with IC50 values ranging from 19 μM – 60 μM. BT treatment resulted in cell cycle arrest at G1/M phase and increased ROS generation [1]. Both bithionol and bithionol sulphoxide demonstrated in vitro toxicity to Neoparamoeba spp. at all concentrations examined (0.1 to 10 mg l(-1) over 72 h), with a comparable toxicity to freshwater observed for both chemicals at concentrations > 5 mg l(-1) following a 72 h treatment [2]. |
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分子量 |
372.05 |
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Formula |
C12H6Cl4O3S |
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CAS 号 |
844-26-8 |
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中文名称 |
硫双二氯酚亚砜 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 250 mg/mL (671.95 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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