Kalii Dehydrographolidi Succinas(Synonyms: 穿琥宁; Potassium dehydroandrographolide succinate)

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Kalii Dehydrographolidi Succinas (Synonyms: 穿琥宁; Potassium dehydroandrographolide succinate) 纯度: 98.70%

Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate),从中药穿心莲中提取,因其具有免疫刺激、抗感染和抗炎作用,有潜力用于病毒性肺炎和病毒性上呼吸道感染的研究。

Kalii Dehydrographolidi Succinas(Synonyms: 穿琥宁; Potassium dehydroandrographolide succinate)

Kalii Dehydrographolidi Succinas Chemical Structure

CAS No. : 76958-99-1

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生物活性

Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect[1][2].

分子量

570.67

Formula

C28H35KO10

CAS 号

76958-99-1

中文名称

穿琥宁

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro: 

DMSO : 5 mg/mL (8.76 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7523 mL 8.7616 mL 17.5233 mL
5 mM 0.3505 mL 1.7523 mL 3.5047 mL
10 mM

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenousadministration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6.

    [2]. Xiaomeng Z, et al. Potassium dehydroandrographolide succinate injection for treat- ment of infantile pneumonia: a systematic review and Meta-analysis. J Tradit Chin Med. 2015 Apr;35(2):125-33.

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