N-(5-Aminopentyl)acetamide(Synonyms: Monoacetylcadaverine)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

N-(5-Aminopentyl)acetamide (Synonyms: Monoacetylcadaverine) 纯度: ≥98.0%

N-(5-Aminopentyl)acetamide 是多胺尸胺的乙酰化形式。

N-(5-Aminopentyl)acetamide(Synonyms: Monoacetylcadaverine)

N-(5-Aminopentyl)acetamide Chemical Structure

CAS No. : 32343-73-0

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ¥770 In-stock
100 mg ¥700 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

N-(5-Aminopentyl)acetamide 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Human Endogenous Metabolite Compound Library
  • Alkaloids Library
  • Gut Microbial Metabolite Library
  • Microbial Metabolite Library
  • Food-Sourced Compound Library

生物活性

N-(5-Aminopentyl)acetamide is the acetylated form of the polyamine cadaverine.

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines, such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmic reactions such as DNA replication and protein synthesis, and are essential for proper growth and proliferation of the organisms[1]. Cadaverine is a linear molecule that terminate at both ends with an amine functional group. These functional groups confer to the molecules multiple positive charges at physiological pH. Cadaverine is produced through the action of basic amino acid decarboxylases and is found associated with the outer membrane[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

144.21

Formula

C7H16N2O

CAS 号

32343-73-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : ≥ 30 mg/mL (208.03 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.9343 mL 34.6717 mL 69.3433 mL
5 mM 1.3869 mL 6.9343 mL 13.8687 mL
10 mM 0.6934 mL 3.4672 mL 6.9343 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Kojima S, et al. Molecular basis for the maintenance of envelope integrity in Selenomonas ruminantium:cadaverine biosynthesis and covalent modification into the peptidoglycan play a major role. J Nutr Sci Vitaminol (Tokyo). 2012;58(3):153-60.

    [2]. Dela Vega AL, et al. Polyamines decrease Escherichia coli outer membrane permeability.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务