Nicotinic acid riboside(Synonyms: 烟酸核糖)

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Nicotinic acid riboside (Synonyms: 烟酸核糖) 纯度: 99.50%

Nicotinic acid riboside 存在于人体细胞中，是一种 NAD+ 前体。Nicotinic acid riboside 是人类 NAD+ 代谢的中间体。

Nicotinic acid riboside(Synonyms: 烟酸核糖)

Nicotinic acid riboside Chemical Structure

CAS No. : 17720-18-2

规格 价格 是否有货 数量
10 mg ￥2800 In-stock
50 mg ￥7500 In-stock
100 mg ￥12000 In-stock
200 mg   询价  
500 mg   询价  

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Nicotinic acid riboside 相关产品

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生物活性

Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism[1][2].

体外研究
(In Vitro)

Nicotinic acid riboside (HepG2 cells; 0.01 nM~0.1 mM) helps FK866-treated cells to maintain viability at low micromolar concentrations[1].
. Nicotinic acid riboside formation and release are caused by overexpression of FLAG-tagged CN-II and CN-III in HEK293 and HepG2 cells. CN-II and CN-III generate Nicotinic acid riboside in vitro by dephosphorylation of nicotinic acid mononucleotide (NAMN)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

255.22

Formula

C11H13NO6
CAS 号

17720-18-2
中文名称

烟酸核糖
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 62.5 mg/mL (244.89 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.9182 mL 19.5909 mL 39.1819 mL
5 mM 0.7836 mL 3.9182 mL 7.8364 mL
10 mM 0.3918 mL 1.9591 mL 3.9182 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Sasaki Y, et al. Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. Exp Neurol. 2021;345:113842.

    [2]. Bogan KL, et al. Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5′-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside [published correction appears in J Biol Chem. 2010 Jan 29;285(5):3524]. J Biol Chem. 2009;284(50):34861-34869.

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