Azetidine-2-carboxylic acid

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Azetidine-2-carboxylic acid  纯度: ≥97.0%

Azetidine-2-carboxylic acid是脯氨酸的非蛋白原氨基酸同系物。 可以在常见的甜菜中找到。 在许多物种（包括人类）中，它可以错误地掺入蛋白质中代替脯氨酸。 致毒和致畸剂。

Azetidine-2-carboxylic acid

Azetidine-2-carboxylic acid Chemical Structure

CAS No. : 2517-04-6

规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥550 In-stock
100 mg ￥500 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Azetidine-2-carboxylic acid 相关产品

•相关化合物库:

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生物活性

Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent[1][2].

体外研究
(In Vitro)

Azetidine-2-carboxylic acid (375-5oo μg per day) is incorporated into the collagen synthesized by chick embryo cartilage in vitro[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

101.10

Formula

C4H7NO2
CAS 号

2517-04-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

H2O : 50 mg/mL (494.56 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 9.8912 mL 49.4560 mL 98.9120 mL
5 mM 1.9782 mL 9.8912 mL 19.7824 mL
10 mM 0.9891 mL 4.9456 mL 9.8912 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Rubenstein E, et al. Azetidine-2-carboxylic acid in the food chain. Phytochemistry. 2009 Jan;70(1):100-4.

    [2]. Rubenstein E, et al. Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis. J Neuropathol Exp Neurol. 2008 Nov;67(11):1035-40.

    [3]. Lane JM, et al. Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. I. Arrest of collagen accumulation in growing chick embryos. Biochim Biophys Acta. 1971 Jun 29;236(3):517-27.

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