上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
ErSO 纯度: 99.75%
ErSO是一种选择性预期折叠蛋白反应 (a-UPR) 激活剂。ErSO 通过 ERα 诱导 a-UPR 产生强而持久的细胞毒性。ErSO 可用于癌症研究。
ErSO Chemical Structure
CAS No. : 2407860-35-7
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥4000 | In-stock | |
10 mg | ¥6800 | In-stock | |
25 mg | ¥13500 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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ErSO 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Anti-Cancer Compound Library
- Orally Active Compound Library
- Anti-Breast Cancer Compound Library
生物活性 |
ErSO is a selective anticipatory unfolded protein response (a-UPR) activator. ErSO acts through ERα to elicit strong and sustained cytotoxic activation of the a-UPR. ErSO can be used for the research of cancer[1]. |
IC50 & Target |
a-UPR[1] |
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体外研究 (In Vitro) |
ErSO (1~1000 nM; 24 hours; MCF-7 cells) shows that IC50 value is 20.3 nM in MCF-7 cells and inhibits cell viability[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
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体内研究 (In Vivo) |
ErSO (10 or 40 mg/kg; p.o.; 21 days) results in elimination of these tumors, with >90% reduction in all cases[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
453.33 |
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Formula |
C22H13F6NO3 |
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CAS 号 |
2407860-35-7 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 120 mg/mL (264.71 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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