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Pomalidomide 4′-PEG5-acid (Synonyms: Pomalidomide-PEG5-CO2H) 纯度: 95.02%
Pomalidomide 4′-PEG5-acid (Pomalidomide-PEG5-CO2H) 是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)，包含基于 Pomalidomide 的 cereblon 配体和 5 个单元 PEG 的 linker。
Pomalidomide 4′-PEG5-acid Chemical Structure
CAS No. : 2139348-63-1
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 50 mg | ￥4000 | In-stock | |
| 100 mg | ￥6500 | In-stock | |
| 200 mg | 询价 | ||
| 500 mg | 询价 |
* Please select Quantity before adding items.
| 生物活性 |
Pomalidomide 4′-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
565.57 |
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| Formula |
C26H35N3O11 |
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| CAS 号 |
2139348-63-1 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
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| 参考文献 |
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