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Etodolac (Synonyms: 依托度酸; AY-24236) 纯度: 99.11%
Etodolac (AY-24236) 是非甾体抗炎化合物,对 COX 的 IC50为53.5 nM。
Etodolac Chemical Structure
CAS No. : 41340-25-4
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥605 | In-stock | |
50 mg | ¥550 | In-stock | |
100 mg | ¥850 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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Etodolac 相关产品
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生物活性 |
Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM) |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other “COX-2 inhibitors.” Unlike rofecoxib, both etodolac and celecoxib can fully inhibit COX-1 and are designated as having “preferential selectivity” toward COX-2. The (inactive against COX) r-enantiomer of etodolac inhibits beta-catenin levels in hepatoma cells. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
287.35 |
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Formula |
C17H21NO3 |
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CAS 号 |
41340-25-4 |
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中文名称 |
依托度酸 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 100 mg/mL (348.01 mM) H2O : < 0.1 mg/mL (insoluble) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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