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beta-Mangostin (Synonyms: β-Mangostin) 纯度: 99.74%
beta-Mangostin (β-Mangostin) 是存在 Cratoxylum arborescens 中的一种氧杂蒽酮化合物,具有抗菌和抗疟疾活性。beta-Mangostin 对结核分枝杆菌作用的 MIC 值为 6.25 μg/mL。beta-Mangostin 具有体外抗疟活性,对恶性疟原虫作用的 IC50 值为 3.00 μg/mL。beta-Mangostin 对各种癌症 (如肝细胞癌、白血病) 具有强大的抗癌活性。
beta-Mangostin Chemical Structure
CAS No. : 20931-37-7
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥2310 | In-stock | |
5 mg | ¥2100 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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beta-Mangostin 相关产品
•相关化合物库:
- Natural Product Library Plus
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- Apoptosis Compound Library
- Natural Product Library
- Anti-Cancer Compound Library
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- Flavonoids Library
- Antiparasitic Compound library
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生物活性 |
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic)[1][2][3][4]. |
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体外研究 (In Vitro) |
beta-Mangostin activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
424.49 |
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Formula |
C25H28O6 |
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CAS 号 |
20931-37-7 |
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中文名称 |
β-倒捻子素 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 25 mg/mL (58.89 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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