上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
BOS-172722 纯度: 99.44%
BOS-172722 是单极纺锤体 1 (MPS1) 检查点的抑制剂,其 对MPS1 (1 mM ATP) 和P-MPS1 的 IC50 值分别为 11 nM 和 63 nM。BOS-172722 可用于多种乳腺癌的研究。
BOS-172722 Chemical Structure
CAS No. : 1578245-44-9
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥2200 | In-stock | |
10 mg | ¥3300 | In-stock | |
25 mg | ¥6600 | In-stock | |
50 mg | ¥9900 | In-stock | |
100 mg | ¥14000 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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BOS-172722 相关产品
•相关化合物库:
- Clinical Compound Library Plus
- Bioactive Compound Library Plus
生物活性 |
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer[1]. |
IC50 & Target |
2 nM (MPS1)[1]. |
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体外研究 (In Vitro) |
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM. BOS-172722 also has potential for the treatment of various forms of breast cancer[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
BOS-172722 shows excellent PK in mouse, rat, and dog[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
446.55 |
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Formula |
C24H30N8O |
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CAS 号 |
1578245-44-9 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
1M HCl : 65 mg/mL (145.56 mM; ultrasonic and adjust pH to 2 with HCl) DMSO : 5 mg/mL (11.20 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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